Product Name Quizartinib
Catalogue No. CM860072
Description Cell-permeable. A second generation FLT3 receptor tyrosine kinase inhibitor. Quizartinib displays high affinity for FLT3 in a binding assay (Kd = 1.6 nM) and is a potent inhibitor in cellular autophosphorylation assays (IC₅₀ = 1.1 nM for FLT3-ITD and 4.2 nM for wt FLT3).  It inhibits the growth of human leukemia cell line MV4-11 (IC₅₀0 = 0.56 nM) which is FLT3 dependent and contains a homozygous FLT3-ITD mutation, and A375 cells (IC50 > 10,000 nM) which are not FLT3 dependent and contain an activating mutation in BRAF. 
CAS Number 950769-58-1
Formula C₂₉H₃₂N₆O₄S
MW 560.67
Grade ≥99% by HPLC
Storage Condition -20°C

Previous Page

Brand Packing Pricing Quote request
IL 1 mg Inquiry Ask Quote
IL 5 mg Inquiry Ask Quote
Advanced Technology & Industrial Co., Ltd. all rights reserved