| Identifiers | ||
| Product Name | PAC-1 | |
| Catalogue No. | CM901494 | |
| Description | Procaspase-activating compound; activates procaspase-3 to produce caspase-3 (EC50 = 0.22 µM). Also activates procaspase-7 in a less efficient manner (EC50 = 4.5 µM). Pro-apoptotic; induces apoptosis in both cancerous and non-cancerous cells dependent on procaspase-3 concentration (IC50 values are 0.003 - 1.41 and 5.02 - 9.98 µM respectively). PAC-1 had an IC50 value of 3 nM for induction of cell death, whereas in cells from adjacent normal tissue IC50 values of 3.2-8.5 µM were observed | |
| CAS Number | 315183-21-2 | |
| Formula | C23H28N4O2 | |
| MW | 392.5 Da | |
| Product Type | Activator | |
| Grade | ≥99% | |
| Storage Condition | refer to Technology Column | |
| Brand | Packing | Pricing | Quote request |
| IL | 10 mg | Inquiry | Ask Quote |
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