| Identifiers | ||
| Product Name | A-769662 | |
| Catalogue No. | CM901508 | |
| Description | A-769662 is a potent, reversible activator of AMP-activated protein kinase (AMPK). AMPK is an αβγ heterotrimer and plays an important role in regulating cellular and whole-body metabolism. A-769662 only activates AMPK heterotrimers containing the β1 subunit. A-769662 activates AMPK through the β subunit carbohydrate-binding module and the γ subunit but not the AMP-binding sites. A-769662 stimulated partially purified rat liver AMPK with an EC50 of 0.8 µM and inhibited fatty acid synthesis in primary rat hepatocytes with an IC50 of 3.2 µM. | |
| CAS Number | 844499-71-4 | |
| Formula | C20H12N2O3S | |
| MW | 360.4 Da | |
| Product Type | Inhibitor | |
| Grade | ≥99% | |
| Storage Condition | refer to Technology Column | |
| Brand | Packing | Pricing | Quote request |
| IL | 5 mg | Inquiry | Ask Quote |
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