| Identifiers | ||
| Product Name | G Protein-Coupled Receptor GPR15 | |
| Catalogue No. | CM525552 | |
| Description | G protein-coupled receptor GPR15 is an Orphan-A GPCR with an unknown ligand. Coreceptor usage of primary human immunodeficiency virus type 1 (HIV-1) isolates varies according to biological phenotype. The chemokine receptors CCR5 and CXCR4 are the major coreceptors that, together with CD4, govern HIV-1 entry into cells. Some HIV-1, HIV-2, and SIV isolates of different genetic subtypes and biological phenotypes use BOB/GPR15 for productive infection, suggesting that this cofactor may play a role in HIV-1 pathogenesis and transmission. GPR15 expression has been reported in CD4(+) T lymphocytes, alveolar macrophages, and the basal surface of the small intestinal epithelium. ESTs have been isolated from normal brain and kidney cancer libraries. | |
| Host | Rabbit | |
| Storage Condition | Long term: -70°C; Short term: -4°C | |
| Brand | Packing | Pricing | Quote request |
| IL | 50 ul | Inquiry | Ask Quote |
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