Identifiers  
Product Name Nuclear Receptor NOR-1 (NR4A3)
Catalogue No. CM525925
Description NOR-1, a NR4 nerve growth factor-like receptor, has been shown to affect neuronal development, T-cell apoptosis, and cancer development. NOR-1 binds to NBRE (NGFI-B response element) and regulates the pro-opiomelanocortin (POMC) gene. NOR-1 is induced rapidly but transiently by a variety of stimuli. Downregulation of NOR-1 and other NGFI-B family members is correlated with drug addiction-prone behavior of Lewis rats. Three human protein isoforms have been documented: NOR-1, NOR-1beta, and NOR-1 3'' variant. NOR-1 expression has been documented in human brain, heart, placenta, kidney, skeletal muscle, fetal brain and fetal lung. ESTs have been isolated from human tissue libraries, including cancerous head/neck and skin, and normal prostate, skin, liver, testis, skeletal muscle, blood and B-cell/lung/testis. Caution: The symbol NOR-1 is also used to describe a nitric oxide-donor reagent. Tec is also the name of a kinase on chromosome 4.
Host Rabbit
Storage Condition Long term: -70°C; Short term: -4°C
 

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