| Identifiers | ||
| Product Name | NVP-TAE684 | |
| Catalogue No. | CM726076 | |
| Description | A potent and selective ALK (anaplastic lymphoma kinase) inhibitor that blocked the growth of ALCL (anaplastic large cell lymphoma)-derived and ALK-dependent cell lines with IC₅₀ = 2-10 nM. NVP-TAE684 treatment resulted in a rapid and sustained inhibition of phosphorylation of NPM-ALK (Nucleophosmin-anaplastic lymphoma kinase) and its downstream effectors and subsequent induction of apoptosis and cell cycle arrest. | |
| Application | 5 mg; CAS# 761439-42-3; A potent and selective ALK (anaplastic lymphoma kinase) inhibitor that blocked the growth of ALCL (anaplastic large cell lymphoma)-derived and ALK-dependent cell lines with IC50 values between 2 and 10 nM. NVP-TAE684 treatment r | |
| CAS Number | 761439-42-3 | |
| Formula | C₃₀H₄₀ClN₇O₃S | |
| MW | 614.2 | |
| Storage Condition | -20°C | |
| Brand | Packing | Pricing | Quote request |
| IL | 5 mg | Inquiry | Ask Quote |
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